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Table 3 Association of depression history with low levels of anti-müllerian hormone (≤1.4 ng/mL), stratified by oral contraceptive use, parity, cycle regularity, smoking and body mass index (BMI), Harvard Study of Moods and Cycles, 1995–1998

From: Association between a history of depression and anti-müllerian hormone among late-reproductive aged women: the Harvard study of moods and cycles

 

AMH Level (≤1.4 ng/mL)

Age-Adjusted

Multivariable Ɨ

n

%

PRa

Adjusted PR (95% CI)

Age, years

 36–40

85

45.2

0.74

0.75

(0.52, 1.09)

 41–45

128

70.7

1.11

1.16

(0.95, 1.40)

Parity (livebirths) c

 Parous

117

58.5

1.07

1.08

(0.85, 1.38)

 Nulliparous

96

56.8

0.78

0.77

(0.59, 1.00)

Infertility

 Fertile

178

58.8

0.96

0.98

(0.81, 1.18)

 Infertile

35

53.0

0.58

0.65

(0.32, 1.33)

Cycle regularity b,c

 Regular Cycle

191

56.2

0.97

0.96

(0.80, 1.16)

 Irregular Cycle

22

75.9

0.75

0.70

(0.38, 1.29)

Baseline smoking status

 Ever-smokers

29

55.8

0.68

0.79

(0.50, 1.26)

 Never-smokers

184

58.0

0.97

0.96

(0.80, 1.16)

Body mass index (BMI), kg/m2

 Normal weight (< 25)

128

56.9

0.87

0.85

(0.68, 1.08)

 Overweight (25-29.9)

55

59.8

1.19

1.22

(0.85, 1.73)

 Obese (≥30)

30

57.7

0.75

0.80

(0.48, 1.35)

  1. Ɨ Covariates included age, age at menarche, irregular cycle, pack years smoking, and body mass index (BMI)
  2. a. ‘Age-adjusted’ model reports crude prevalence ratios for stratified age-groups
  3. b. Did not adjust for parity
  4. c. Did not adjust for oral contraceptive use