Skip to main content

Table 2 Promising intervention components to prevent, delay, or mitigate functional impairment in middle-aged adults

From: Moving prevention of functional impairment upstream: is middle age an ideal time for intervention?

Intervention components

Exemplar intervention for older adults and impact

Target population

Structured exercise programs including aerobic training, resistance training, and flexibility training

Lifestyle Interventions and Independence for Elders (LIFE) Study Randomized Clinical Trial; reduced risk of major mobility disability in at-risk older adults

May benefit middle-aged individuals whose main risk factor for functional impairment is reduced strength and physical performance, including post-menopausal women

Multi-component interventions addressing deficits related to physical capability and to environmental demand and adaptation

Community Aging in Place – Advancing Better Living for Elders (CAPABLE) study; reduced ADL disability scores in at-risk group

May benefit middle-aged individuals with multiple risk factors for functional impairment, including reduced physical performance and social and environmental risks