| |
Model 1
| |
Model 2
| |
|---|
|
Variable
|
PR (95% CI)
|
p-value
|
PR (95% CI)
|
p-value
|
|---|
|
rs 1205
|
|
CC
|
1.64 (1.15–2.33)
|
0.006
|
1.53 (1.07–2.18)
|
0.018
|
|
T carriers
|
1
| |
1
| |
|
MS
|
|
Yes
|
1.50 (1.05–2.15)
|
0.025
|
1.19 (0.79–1.80)
|
0.404
|
|
No
|
1
| |
1
| |
|
Age, years
|
1.03 (1.01–1.06)
|
0.024
|
1.02 (0.99–1.06)
|
0.224
|
|
IL6, pg/mL
|
1.03 (1.01–1.05)
|
0.003
|
1.02 (0.99–1.04)
|
0.052
|
|
HOMA-IR
|
1.07 (0.99–1.16)
|
0.085
| | |
|
SBP, mmHg
|
1.01 (1.002–1.02)
|
0.013
|
1.00 (0.99–1.02)
|
0.967
|
|
HDL-c, mg/dl
|
0.98 (0.97–0.99)
|
0.024
|
1.00 (0.98–1.02)
|
0.943
|
|
Triglycerides, mg/dl
|
1.001 (1.000–1.002)
|
0.052
| | |
|
Insulin, μUI/ml
|
1.01 (0.99–1.03)
|
0.122
| | |
|
HT
|
|
Yes
|
0.66 (0.42–1.04)
|
0.072
| | |
|
No
|
1
| | | |
|
WC
|
|
< 88 cm
|
1
| |
1
| |
|
≥ 88 cm
|
2.46 (1.67–3 64)
|
< 0.001
|
2.45 (1.66–3.60)
|
< 0.001
|
- hs-CRP high-sensitivity C-reactive protein, SBP systolic blood pressure, HT hormone therapy, MS metabolic syndrome, WC waist circumference, HOMA-IR homeostatic model assessment, IL6 interleukin 6, PR prevalence ratio, CI confidence interval
- Model 1: PR for each variable
- Model 2: multivariable Poisson regression including all the variables that were significant in the univariable analysis. Only the polymorphism and waist circumference remained significant in the final model
