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Table 3 Anthropometric, clinical and metabolic characteristics according to rs1205

From: C-reactive protein gene rs1205 polymorphism is associated with low-grade chronic inflammation in postmenopausal women

 

rs1205

 

Variable

CC (n = 129)

T carriers (n = 198)

p-value

Age, years

55.4 ± 5.3

55.7 ± 5.7

0.596a

Time since menopause, years

5 (2–10)

5 (2–12)

0.978a

Waist circumference, cm

 WC < 88 cm

39.5% (73)

40.2% (53)

0.994b

 WC ≥ 88 cm

60.5% (112)

59.8% (79)

Body mass index, kg/m2 (n = 316)c

  < 24.9

31.2% (39)

36.1% (69)

0.633b

 25–30

44.8% (56)

42.9% (82)

  > 30

24.0% (30)

20.9% (40)

SBP, mmHg

125.9 ± 17.8

126.2 ± 18.7

0.902a

DBP, mmHg

80.2 ± 11.5

79.7 ± 11.7

0.714a

Total cholesterol, mg/dl

207.2 ± 46.1

210.5 ± 43.7

0.510a

HDL-c, mg/dl

55.7 ± 12.7

58.8 ± 14.6

0.300a

LDL-c, mg/dl

124.5 ± 40.2

127.5 ± 34.5

0.476a

Triglycerides, mg/dl

140.7 ± 141.8

139.6 ± 118.2

0.938a

Glucose, mg/dl

93.1 ± 18.3

94.2 ± 24.3

0.662a

HOMA-IR

1.7 (1.3–2.3)

1.8 (1.2–2.7)

0.229a

Insulin, μUI/ml

7.3 (5.7–9.8)

8.0 (5.6–11.6)

0.354a

Metabolic syndrome, % (n)

31.8% (41)

28.1% (55)

0.552b

hs-CRP, mg/l

2.1 (1.0–3.9)

1.5 (0.63–2.6)

0.004a

IL6, pg/mL (n = 279)c

1.13 (0.85–1.79)

1.13 (0.76–1.74)

0.285a

HT, % (n)

28.7% (37)

29.3% (58)

0.999b

  1. Values are expressed as (± standard deviation) or median (interquartile range) (25–75%) (aStudent’s t test) or percentage (absolute number) (bχ2 test, with continuity correction when applicable). cNumber of subjects in sub-sample analyses. P-value of nonparametric variables was obtained after logarithmic transformation. SBP systolic blood pressure, DBP diastolic blood pressure, HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol, HOMA-IR homeostatic model assessment, hs-CRP high-sensitivity C-reactive protein, HT hormone therapy, IL6 interleukin 6