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Table 2 Anthropometric, clinical and metabolic characteristics according to hs-CRP levels

From: C-reactive protein gene rs1205 polymorphism is associated with low-grade chronic inflammation in postmenopausal women

  hs-CRP
Variable < 3 mg/l (n = 238) ≥3 mg/l (n = 89) p-value
Age, years 55.2 ± 5.5 56.7 ± 5.6 0.029a
Time since menopause, years 4 (2–10) 7 (2–12) 0.157a
White participants, % (n) 88.6% (210) 85.1% (74) 0.503b
Waist circumference, cm (n = 292)c
 WC < 88 cm 66.35% (140) 35.80% (29) < 0.001b
 WC ≥ 88 cm 33.65% (71) 64.20% (52)
Body mass index, kg/m2 (n = 287)c
  < 24.9 41% (85) 17.50% (14) < 0.001b
 25–30 44% (91) 41.25% (33)
  > 30 15% (31) 41.25% (33)
SBP, mmHg 125.8 ± 17.4 131.2 ± 19.3 0.021a
DBP, mmHg 79.7 ± 11.1 82.2 ± 11.7 0.084a
Total cholesterol, mg/dl 214.6 ± 41.9 212.2 ± 48.1 0.662a
HDL-c, mg/dl 58.3 ± 14.4 54.4 ± 11.8 0.030a
LDL-c, mg/dl 130.4 ± 36.3 126.5 ± 36.7 0.410a
Triglycerides, mg/dl 115 (76–157) 131 (97–173) 0.018a
Glucose, mg/dl 94.1 ± 24.8 93.4 ± 18.3 0.946a
HOMA-IR 1.6 (1.2–2.4) 2.1 (1.5–3.1) 0.026a
Insulin, μUI/ml 7.4 (5.5–10.1) 9.1 (6.6–13.2) 0.019a
Metabolic syndrome, % (n) 26.2% (62) 38.6% (34) 0.040b
IL6, pg/mL (n = 279)c 1.02 (0.73–1.56) 1.43 (1.08–2.44) < 0.001a
HT, % (n) 32% (76) 21% (19) 0.082b
 Oral (n = 54)c 65.7% (44) 52.6% (10) 0.442b
 Non-oral (n = 32)c 34.3% (23) 47.4% (9)
T carriers, % (n) 65% (155) 48% (43) 0.008b
  1. Values are expressed as mean (± standard deviation) or median (interquartile range) (25–75%) (aStudent’s t test) or percentage (absolute number) (bχ2 test, with continuity correction when applicable). cNumber of subjects in sub-sample analyses. P-value of nonparametric variables was obtained after logarithmic transformation. Percentages of hs-CRP levels to categorical variables are shown in the rows. SBP systolic blood pressure, DBP diastolic blood pressure, HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol, HOMA-IR homeostatic model assessment. HT hormone therapy, IL6 interleukin 6
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Women's Midlife Health

ISSN: 2054-2690

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