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Table 2 Anthropometric, clinical and metabolic characteristics according to hs-CRP levels

From: C-reactive protein gene rs1205 polymorphism is associated with low-grade chronic inflammation in postmenopausal women

 

hs-CRP

Variable

< 3 mg/l (n = 238)

≥3 mg/l (n = 89)

p-value

Age, years

55.2 ± 5.5

56.7 ± 5.6

0.029a

Time since menopause, years

4 (2–10)

7 (2–12)

0.157a

White participants, % (n)

88.6% (210)

85.1% (74)

0.503b

Waist circumference, cm (n = 292)c

 WC < 88 cm

66.35% (140)

35.80% (29)

< 0.001b

 WC ≥ 88 cm

33.65% (71)

64.20% (52)

Body mass index, kg/m2 (n = 287)c

  < 24.9

41% (85)

17.50% (14)

< 0.001b

 25–30

44% (91)

41.25% (33)

  > 30

15% (31)

41.25% (33)

SBP, mmHg

125.8 ± 17.4

131.2 ± 19.3

0.021a

DBP, mmHg

79.7 ± 11.1

82.2 ± 11.7

0.084a

Total cholesterol, mg/dl

214.6 ± 41.9

212.2 ± 48.1

0.662a

HDL-c, mg/dl

58.3 ± 14.4

54.4 ± 11.8

0.030a

LDL-c, mg/dl

130.4 ± 36.3

126.5 ± 36.7

0.410a

Triglycerides, mg/dl

115 (76–157)

131 (97–173)

0.018a

Glucose, mg/dl

94.1 ± 24.8

93.4 ± 18.3

0.946a

HOMA-IR

1.6 (1.2–2.4)

2.1 (1.5–3.1)

0.026a

Insulin, μUI/ml

7.4 (5.5–10.1)

9.1 (6.6–13.2)

0.019a

Metabolic syndrome, % (n)

26.2% (62)

38.6% (34)

0.040b

IL6, pg/mL (n = 279)c

1.02 (0.73–1.56)

1.43 (1.08–2.44)

< 0.001a

HT, % (n)

32% (76)

21% (19)

0.082b

 Oral (n = 54)c

65.7% (44)

52.6% (10)

0.442b

 Non-oral (n = 32)c

34.3% (23)

47.4% (9)

T carriers, % (n)

65% (155)

48% (43)

0.008b

  1. Values are expressed as mean (± standard deviation) or median (interquartile range) (25–75%) (aStudent’s t test) or percentage (absolute number) (bχ2 test, with continuity correction when applicable). cNumber of subjects in sub-sample analyses. P-value of nonparametric variables was obtained after logarithmic transformation. Percentages of hs-CRP levels to categorical variables are shown in the rows. SBP systolic blood pressure, DBP diastolic blood pressure, HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol, HOMA-IR homeostatic model assessment. HT hormone therapy, IL6 interleukin 6