Is in utero exposure to maternal socioeconomic disadvantage related to offspring ovarian reserve in adulthood?

Women's Midlife Health

Table 3 Final multivariate linear regression models examining maternal neighborhood characteristics during pregnancy and offspring ovarian reserve in adulthood, adjusted for covariates.* Results show variables remaining in the models after backward elimination of main effects with P > .10

			DV: AMH
	Beta	P	b	95% CI for b
1. Predictors:
Age	−.318	.000	−.040	(− 0.052, − 0.028)
BMI	−.170	.001	−.472	(−0.748, − 0.196)
Maternal Neighborhood:
Education (% of individuals with a HS diploma)	.142	.006	.588	(0.168, 1.008)
2. Predictors:
Age	−.382	.000	−.048	(−0.061, −0.035)
BMI	−.157	.003	−.435	(−0.719, − 0.152)
Maternal Neighborhood:
Poverty (% of families below the poverty line)	−.144	.007	−1.033	(−1.778, −0.288)
3. Predictors: Maternal Neighborhood:
Unemployment (% of unemployed individuals)	–	n.s.	–	–
4. Predictors: Maternal Neighborhood:
Income (median family income)	–	n.s.	–	–
			DV: AFC
	Beta	P	b	95% CI for b
1. Predictors:
Age	−.398	.000	−.086	(−0.107, −0.064)
Hormonal contraceptives	−.119	.017	−.338	(−0.616, − 0.061)
Maternal Neighborhood:
Education (% of individuals with a HS diploma)	.092	.064	.649	(−0.038, 1.337)
2. Predictors: Maternal Neighborhood:
Poverty (% of families below the poverty line)	–	n.s.	–	–
3. Predictors: Maternal Neighborhood:
Unemployment (% of unemployed individuals)	–	n.s.	–	–
4. Predictors: Maternal Neighborhood:
Income (median family income)	–	n.s.	–	–

*Covariates examined simultaneously included age (in years); maternal age (in years); race/ethnicity (using white as the reference group vs. African-American, Latina, Chinese, or Filipina); educational attainment (using HS degree or less as the reference group vs. some college, college degree, or graduate degree); smoking (0 = never smoked, 1 = current/past smoking); BMI (kg/m², log transformed); menarcheal age (in years); hormonal contraceptives (0 = no history of use, 1 = positive history of use; and parity (0 = no live births, 1 = 1+ live births)

ISSN: 2054-2690