Depressed mood during the menopausal transition: is it reproductive aging or is it life?

Women's Midlife Health

Table 3 Random effects models for depressed mood severity with age as predictor (β₂) and with individual covariates (β₃)

	Mean Values (p values)			Standard Deviations			Number
Predictor	β₁ ^a	β₂ ^a	β₃ ^a	σ₁ ^b	σ₂ ^b	σ_ε ^b	Women	Observations
Age (47.7)	0.51	<0.001 (0.84)	–	0.49	0.03	0.60	291	6977
Menopausal Transition Factors
MT-stage	0.52 (<.001)	0.005 (0.25)		0.49	0.03	0.60	291	6977
Early			0.02 (0.56)
Late			−0.006 (0.88)
Early PM			−0.10 (0.05)
Estrone (1.3)	0.62 (<.001)	−0.01 (0.04)	−0.03 (0.32)	0.50	0.04	0.60	131	4908
FSH (1.1)	0.58 (<.001)	−0.01 (0.04)	−0.02 (0.23)	0.50	0.04	.060	131	4996
Health-related factors
BMI (26.0)	0.37 (<.001)	<0.001 (0.97)	0.005 (0.20)	0.49	0.03	0.60	291	6977
If drinks alcohol	0.51 (<.001)	<0.001 (0.84)	−0.001 (0.97)	0.49	0.03	0.60	291	6977
Amount of exercise	0.54 (<.001)	0.001 (0.69)	−0.001 (<.001)	0.49	0.03	0.60	291	6977
Social factors
If partnered	0.58 (<.001)	<0.001 (0.87)	−0.11 (0.002)	0.49	0.03	0.60	291	6977
Number of live births	0.51 (<.001)	<0.001 (0.83)	−0.002 (0.93)	0.49	0.03	0.60	291	6977
Stress
Perceived Stress	0.06 (0.10)	0.008 (0.02)	0.18 (<.001)	0.47	0.03	0.58	291	6977
History of sexual abuse	0.42 (<.001)	<0.001 (0.82)	0.25 (<.001)	0.47	0.03	0.60	234	6766
Symptoms
Hot flashes	0.50 (<.001)	<0.001 (0.88)	0.003 (0.78)	0.49	0.03	0.60	291	6977
Problem getting to sleep	0.42 (<.001)	−0.0003 (0.91)	0.24 (<.001)	0.44	0.03	0.59	291	6977
Early awakening	0.44 (<.001)	−0.003 (0.41)	0.13 (<.001)	0.47	0.03	0.59	291	6977
Awaken at Night	0.43 (<.001)	−0.002 (0.50)	0.11 (<.001)	0.47	.03	0.59	291	6977

^aβ_1, β_2, β₃ are the fixed effects (group averages) for the intercept, slope and covariate
^bσ_1, σ_2, σ_ε are the random effects (variability) for the intercept, slope and residual error

ISSN: 2054-2690