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Table 2 Main results of the PFS

From: The Passo Fundo Cohort Study: design of a population-based observational study of women in premenopause, menopausal transition, and postmenopause

Author, year

Study design

N participants

Objective

Conclusion

Oppermann et al. 2003 [33]

Cross-sectional

98

To evaluate the relationship between ovarian volume and age, hormone levels, obesity, and menstrual cycle phase in pre- and perimenopausal women.

Ovarian volume was smaller in pre- and perimenopausal women aged 40 years or older compared with younger women.

Bastos et al. 2006 [5]

Cross-sectional

273

To investigate the association of smoking, parity, BMI, oral contraceptive use, and hormone therapy with ovarian volume in pre-, transition, and postmenopausal women.

Obesity was positively related to ovarian volume, menopausal status, and age. Use of contraception was associated with reduced ovarian volume.

Donato et al. 2006 [6]

Cross-sectional

358

To investigate the association between menopausal status and central adiposity measured by two different cutoffs of waist circumference and waist-to-hip ratio.

Postmenopausal women were at greater risk of having central adiposity (waist circumference and waist-to-hip ratio) than premenopausal women.

Oppermann et al. 2012 [15]

Cross-sectional

324

To identify the prevalence of physical, psychological, and menopause-related symptoms and their association with minor psychiatric disorders in pre-, peri-, and postmenopausal women.

Low level of education, memory loss, irritability, and menopausal transition were risk factors for positive findings in screening for minor psychiatric disorders.

Colpani et al. 2012 [7]

Cross-sectional

292

To assess pedometer-determined habitual physical activity in a Brazilian cohort of pre-, peri-, and postmenopausal women and its effect on anthropometric measurements and cardiovascular risk factors.

Walking 6,000 or more steps daily was associated with a decreased risk of CVD and DM in middle-aged women, regardless of menopausal status.

Colpani et al. 2014 [34]

Cross-sectional

292

To compare two methods of assessing physical activity in pre-, peri-, and postmenopausal women.

The agreement (k = 0110; p = 0.007) and correlation (rho = 0.136, p = 0.02) between the IPAQ-SF and the pedometer were weak.

Colpani et al. 2014 [35]

Longitudinal

358n

To assess mortality rate, causes of death, and associated risk factors in climacteric women.

CVD was an important cause of death in this cohort. DM and/or central adiposity were associated with all-cause mortality.

  1. BMI body mass index, CVD cardiovascular disease, DM diabetes mellitus, IPAQ-SF International Physical Activity Questionnaire-Short Form