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Table 2 Main results of the PFS

From: The Passo Fundo Cohort Study: design of a population-based observational study of women in premenopause, menopausal transition, and postmenopause

Author, year Study design N participants Objective Conclusion
Oppermann et al. 2003 [33] Cross-sectional 98 To evaluate the relationship between ovarian volume and age, hormone levels, obesity, and menstrual cycle phase in pre- and perimenopausal women. Ovarian volume was smaller in pre- and perimenopausal women aged 40 years or older compared with younger women.
Bastos et al. 2006 [5] Cross-sectional 273 To investigate the association of smoking, parity, BMI, oral contraceptive use, and hormone therapy with ovarian volume in pre-, transition, and postmenopausal women. Obesity was positively related to ovarian volume, menopausal status, and age. Use of contraception was associated with reduced ovarian volume.
Donato et al. 2006 [6] Cross-sectional 358 To investigate the association between menopausal status and central adiposity measured by two different cutoffs of waist circumference and waist-to-hip ratio. Postmenopausal women were at greater risk of having central adiposity (waist circumference and waist-to-hip ratio) than premenopausal women.
Oppermann et al. 2012 [15] Cross-sectional 324 To identify the prevalence of physical, psychological, and menopause-related symptoms and their association with minor psychiatric disorders in pre-, peri-, and postmenopausal women. Low level of education, memory loss, irritability, and menopausal transition were risk factors for positive findings in screening for minor psychiatric disorders.
Colpani et al. 2012 [7] Cross-sectional 292 To assess pedometer-determined habitual physical activity in a Brazilian cohort of pre-, peri-, and postmenopausal women and its effect on anthropometric measurements and cardiovascular risk factors. Walking 6,000 or more steps daily was associated with a decreased risk of CVD and DM in middle-aged women, regardless of menopausal status.
Colpani et al. 2014 [34] Cross-sectional 292 To compare two methods of assessing physical activity in pre-, peri-, and postmenopausal women. The agreement (k = 0110; p = 0.007) and correlation (rho = 0.136, p = 0.02) between the IPAQ-SF and the pedometer were weak.
Colpani et al. 2014 [35] Longitudinal 358n To assess mortality rate, causes of death, and associated risk factors in climacteric women. CVD was an important cause of death in this cohort. DM and/or central adiposity were associated with all-cause mortality.
  1. BMI body mass index, CVD cardiovascular disease, DM diabetes mellitus, IPAQ-SF International Physical Activity Questionnaire-Short Form