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Table 4 Effect of surgical treatments of urge urinary incontinence on sexual function

From: Impact of urinary incontinence on female sexual health in women during midlife

Author

Study Design

N

Treatment

Instrument

Findings

Obotulinumtoxin A injection

Nitti et al [77]

RCT

1. Placebo: 243

1. Placebo

KHQ (Personal Relationship Domain)

• Clinically significant improvement in all KHQ scores, including Personal Relationship (-13.4 v -1.1, p < 0.001)

2. Botox: 249

2. Botox 100 U follow up: 12 weeks

Sacral neuromodulation

Zahibi et al [78]

Prospective case series

36

SNM follow up: 6 months

FSFI

• Significant ↑ FSFI total and all subscale scores except desire

• Pts with voiding dysfunction only: 157 % improvement in total FSFI

Signorello et al [79]

Prospective case series

30

SNM follow up: median 36.3 months

FSFI

• Significant improvement in total FSFI and most domains except orgasm

• 25 % showed >50 % improvement on total FSFI

Gill et al [80]

Prospective case series

8

SNM follow up: median 3.2 months

FSFI, Female Sexual Health Questionnaire

• Significant improvement in arousal, satisfaction, orgasm

• 50 % ↓ CI, restriction of SA due to UI

Pauls et al [81]

Prospective case series

7

SNM

FSFI

• Significant ↑ frequency, improvement of FSFI total and desire, lubrication, satisfaction, pain scores

Ingber et al [82]

Prospective case series

27

SNM follow up: 6 months

FSFI

• Non-significant improvement in FSFI in OAB patients (18.6 → 22.4, p = 0.257)

  1. SA Sexual activity, FSFI Female Sexual Function Index; KHQ King’s Health Questionnaire; CI Coital incontinence; RCT Randomized controlled trial; SNM Sacral neuromodulation