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Table 4 Effect of surgical treatments of urge urinary incontinence on sexual function

From: Impact of urinary incontinence on female sexual health in women during midlife

Author Study Design N Treatment Instrument Findings
Obotulinumtoxin A injection
Nitti et al [77] RCT 1. Placebo: 243 1. Placebo KHQ (Personal Relationship Domain) • Clinically significant improvement in all KHQ scores, including Personal Relationship (-13.4 v -1.1, p < 0.001)
2. Botox: 249 2. Botox 100 U follow up: 12 weeks
Sacral neuromodulation
Zahibi et al [78] Prospective case series 36 SNM follow up: 6 months FSFI • Significant ↑ FSFI total and all subscale scores except desire
• Pts with voiding dysfunction only: 157 % improvement in total FSFI
Signorello et al [79] Prospective case series 30 SNM follow up: median 36.3 months FSFI • Significant improvement in total FSFI and most domains except orgasm
• 25 % showed >50 % improvement on total FSFI
Gill et al [80] Prospective case series 8 SNM follow up: median 3.2 months FSFI, Female Sexual Health Questionnaire • Significant improvement in arousal, satisfaction, orgasm
• 50 % ↓ CI, restriction of SA due to UI
Pauls et al [81] Prospective case series 7 SNM FSFI • Significant ↑ frequency, improvement of FSFI total and desire, lubrication, satisfaction, pain scores
Ingber et al [82] Prospective case series 27 SNM follow up: 6 months FSFI • Non-significant improvement in FSFI in OAB patients (18.6 → 22.4, p = 0.257)
  1. SA Sexual activity, FSFI Female Sexual Function Index; KHQ King’s Health Questionnaire; CI Coital incontinence; RCT Randomized controlled trial; SNM Sacral neuromodulation